Usted esta aquí
Inicio > Avances Médicos > Biomarcador de asma podría conducir al desarrollo de una prueba mínimamente invasiva

Biomarcador de asma podría conducir al desarrollo de una prueba mínimamente invasiva

Un grupo de investigadores de la Escuela de Medicina de Icahn en Mount Sinai, en la ciudad de Nueva York (líder internacional en capacitación médica y científica, investigación biomédica y atención al paciente) han identificado un biomarcador genético para el asma que se puede analizar utilizando un simple copito de algodón y un análisis de datos de seguimiento básico. Esta prueba de diagnóstico de bajo costo puede identificar con precisión el asma leve a moderada y diferenciarla de otras afecciones respiratorias como la rinitis alérgica, el tabaquismo, la infección de las vías respiratorias superiores y la fibrosis quística. El equipo de investigación fue liderado por una colaboración de científicos clínicos y computacionales en el Departamento de Genética y Ciencias Genómicas, el Instituto Icahn de Genómica y Biología Multiescala, y el Departamento de Pediatría de la Facultad de Medicina Icahn en Mount Sinai.

Actualmente, la prueba de función pulmonar (PFT) es la herramienta de diagnóstico más confiable para el asma. Sin embargo, el equipo y la experiencia necesarios para realizar estas pruebas no siempre están disponibles en entornos de atención primaria donde el asma se diagnostica y trata con frecuencia. También es difícil diferenciar entre asma y otras enfermedades respiratorias usando PFT solo, mientras que el copito de algodón y el posterior análisis de este biomarcador de asma, proporciona un resultado binario de asma o no de asma.

Los científicos de datos que lideraron el estudio aplicaron algoritmos de aprendizaje automático a los datos genéticos (ARN) adquiridos de los copitos de algodón de pacientes con y sin asma. Esta robusta recopilación de datos y el análisis de aprendizaje automático identificaron un biomarcador de 90 genes indicativo del estado del asma.

El próximo paso para llevar esta prueba a la práctica clínica es un estudio en una población más grande de pacientes.

Más información: Escuela de Medicina de Icahn en Mount Sinai

21 thoughts on “Biomarcador de asma podría conducir al desarrollo de una prueba mínimamente invasiva

  1. I actually wanted to write down a quick remark so as to thank you for the nice ways you are sharing at this site. My considerable internet investigation has at the end of the day been paid with beneficial knowledge to exchange with my good friends. I ‘d claim that most of us readers are unequivocally blessed to be in a useful website with many awesome people with good tricks. I feel really lucky to have encountered the website page and look forward to some more enjoyable minutes reading here. Thanks once again for everything.

  2. I have to show my passion for your generosity in support of all those that must have help with the matter. Your special commitment to passing the solution all-around had become incredibly powerful and have truly empowered workers like me to achieve their goals. This warm and friendly report can mean much a person like me and extremely more to my fellow workers. Warm regards; from everyone of us.

  3. Thanks a lot for giving everyone an extraordinarily splendid chance to read from this site. It is often so sweet and as well , packed with a good time for me personally and my office acquaintances to visit your blog nearly thrice per week to find out the latest guides you have got. Of course, I’m so at all times astounded considering the surprising guidelines you give. Certain 4 points in this posting are completely the most suitable we’ve had.

  4. Needed to post you one bit of observation to give thanks as before on the marvelous guidelines you’ve shared above. It is simply particularly open-handed of you to allow unhampered what exactly a number of us could possibly have distributed as an e book to make some cash for their own end, precisely seeing that you could have tried it if you considered necessary. Those solutions as well worked like a easy way to be certain that someone else have a similar interest just like my own to know the truth more when it comes to this matter. I think there are thousands of more pleasant instances in the future for those who discover your blog post.

  5. I as well as my friends ended up looking through the best strategies located on your website while immediately came up with a terrible feeling I had not expressed respect to the website owner for them. The guys came totally passionate to read all of them and have now really been enjoying those things. Thank you for being quite helpful and then for making a decision on this sort of beneficial subject areas millions of individuals are really eager to understand about. Our honest regret for not saying thanks to you sooner.

  6. I together with my friends appeared to be reading the nice tips and tricks on your website while unexpectedly I had a terrible feeling I never expressed respect to the web site owner for those tips. The young boys came so passionate to learn all of them and have now absolutely been taking advantage of them. I appreciate you for being quite considerate as well as for finding variety of beneficial themes millions of individuals are really desperate to discover. My sincere apologies for not saying thanks to you earlier.

  7. I precisely desired to thank you so much once more. I’m not certain the things that I would’ve tried without the methods provided by you on this situation. It was actually a real challenging situation in my circumstances, however , seeing this skilled approach you managed the issue forced me to weep over happiness. Now i’m thankful for the work as well as have high hopes you realize what an amazing job you are always carrying out instructing people through your site. I am sure you’ve never come across any of us.

  8. I in addition to my friends appeared to be reading the good secrets found on your website and so before long got a terrible feeling I had not expressed respect to the web blog owner for those secrets. Most of the men came totally glad to learn them and have now unquestionably been taking pleasure in these things. Thanks for turning out to be quite considerate and also for obtaining some essential subject matter most people are really needing to be informed on. Our own honest apologies for not saying thanks to you earlier.

  9. I precisely had to thank you very much all over again. I’m not certain the things I would have gone through without the actual creative ideas documented by you regarding my situation. It was before a real difficult matter in my circumstances, but observing the expert technique you treated it forced me to cry over joy. Now i’m happier for your assistance and even wish you know what a powerful job that you are putting in training others thru your blog post. I’m certain you haven’t met any of us.

  10. Thanks for all your efforts on this blog. My mom really loves managing investigations and it is obvious why. Almost all hear all concerning the lively way you give simple items through the website and as well attract contribution from the others about this content then my simple princess is always becoming educated a whole lot. Enjoy the remaining portion of the year. You’re conducting a good job.

  11. I have to show my love for your generosity giving support to those who should have help on that concern. Your personal commitment to getting the message along came to be extremely beneficial and has continually allowed people much like me to realize their endeavors. Your entire useful instruction signifies a great deal a person like me and even more to my office colleagues. Warm regards; from each one of us.

  12. I precisely desired to appreciate you once again. I am not sure the things I might have created without the entire recommendations shown by you about this topic. Certainly was a intimidating problem in my circumstances, nevertheless understanding this specialized fashion you handled that made me to weep with delight. I will be happier for this service and hope you are aware of a great job you are always carrying out instructing many people all through a site. I’m certain you haven’t got to know any of us.

  13. I and also my friends appeared to be checking out the good pointers located on the website then quickly I had an awful feeling I never expressed respect to the blog owner for those strategies. My young boys happened to be totally happy to see them and have in effect unquestionably been taking pleasure in those things. Thank you for being really helpful and also for settling on some remarkable tips millions of individuals are really desperate to be aware of. Our own honest regret for not expressing appreciation to sooner.

  14. Thank you a lot for providing individuals with an extremely breathtaking opportunity to read critical reviews from this site. It is usually so pleasant and packed with amusement for me personally and my office mates to visit your blog the equivalent of three times every week to read the latest guides you will have. And lastly, I’m also usually pleased considering the eye-popping suggestions served by you. Some 2 areas in this article are essentially the most beneficial we’ve had.

  15. Thank you a lot for providing individuals with an extremely special opportunity to read critical reviews from this website. It can be so ideal and also packed with fun for me personally and my office acquaintances to search your website no less than thrice in one week to learn the fresh stuff you have got. And of course, I’m just certainly pleased considering the brilliant inspiring ideas you serve. Certain 2 ideas in this article are unequivocally the most beneficial we have all ever had.

  16. I and my buddies came reviewing the nice guides located on your web page while before long came up with an awful suspicion I never expressed respect to you for those techniques. All the people happened to be absolutely joyful to learn all of them and now have undoubtedly been taking advantage of them. Thank you for indeed being quite thoughtful and then for deciding upon some essential tips most people are really wanting to understand about. My very own sincere apologies for not saying thanks to earlier.

  17. I’m just writing to make you understand of the great experience my cousin’s daughter encountered checking your site. She noticed too many things, including how it is like to possess an excellent teaching nature to get certain people without difficulty know just exactly several multifaceted matters. You really did more than our own desires. Thanks for providing those effective, safe, informative and in addition unique thoughts on your topic to Emily.

  18. I want to show my appreciation to the writer just for bailing me out of this particular problem. Because of browsing through the internet and finding things which are not productive, I was thinking my life was over. Living minus the answers to the issues you have solved all through your entire blog post is a crucial case, as well as those that might have in a negative way affected my career if I hadn’t come across your website. Your own personal competence and kindness in taking care of all areas was invaluable. I am not sure what I would’ve done if I had not encountered such a point like this. I’m able to now look ahead to my future. Thanks very much for your expert and results-oriented guide. I won’t be reluctant to propose your web blog to any person who should receive assistance on this issue.

  19. I precisely wanted to appreciate you again. I’m not certain what I could possibly have carried out in the absence of the pointers discussed by you directly on such a situation. It was a daunting difficulty in my circumstances, however , taking note of a professional tactic you solved it made me to weep over fulfillment. I’m just thankful for this assistance as well as hope you know what a great job you happen to be carrying out teaching the others by way of your blog. I’m certain you’ve never come across any of us.

  20. I and my buddies were viewing the great techniques found on your web blog then before long developed a horrible suspicion I had not thanked the blog owner for those strategies. These men became as a consequence thrilled to learn them and now have unquestionably been having fun with them. Appreciate your indeed being indeed accommodating as well as for getting these kinds of very good topics millions of individuals are really wanting to learn about. Our own sincere apologies for not saying thanks to earlier.

  21. I precisely desired to appreciate you yet again. I do not know what I could possibly have gone through in the absence of the type of tactics provided by you directly on that area of interest. Entirely was a real challenging case in my circumstances, however , spending time with a new specialised style you resolved that took me to jump over contentment. I’m just thankful for the guidance and then hope that you really know what an amazing job your are carrying out teaching other individuals through a web site. Probably you haven’t met all of us.

Deja un comentario

Top